The support interference in wing in ground effect wind tunnel test was simulated and analyzed by using computational fluid dynamics(CFD)method.The wing model NACA 0012 was applied.Because of the symmetry the half model was simulated.The cases of separate sup-port,the wing with and without support were simulated separately.The steady imcompressible Navier-Stokes equation and realizableκ-εmodel were used.The semi-infinite computational do-main was calculated.The floor was divided into two different parts,one part was fixed using wall boundary condition,and the other part was moving belt which was set with moving wall bounda-ry condition.Aerodynamic forces of frame and wing with interference were studied by analyzing the aerodynamic interference and flow field interference separately,and we got some conclusions. On one hand,the interference between frame and wing was increased with the increase of the wing’s attack angle.On the other hand,if the interference from flowing air was ignored,the er-ror for lift force of wing was little while that for drag force was large.Then flows with and with-out interference were compared with each other in order to study the effect of interference on de-velopment of wingtip vortex and flow around the wing.Within the area around 0.5c far from wingtip the wingtip vortex was almost not affected.The viscous flow near steady ground outside the moving belt had some effects on the flow around wing.The current study evaluates the relia-bility of test results in wind tunnel test and provides reference for optimization of wing in ground effect wind tunnel test and experimental investigation of ground effect.